Solid oral forms availability in children: a cost saving investigation
نویسندگان
چکیده
منابع مشابه
The challenges of solid oral forms formulation
Piero Iamartino coordinates the new AFI’s Pharmaceutical Technology working group, together with professor Andrea Gazzaniga of the University of Milan. He summarizes for Pharma World the history and final goals of the MCS initiative, originally proposed in 2014 by a British university-industry mixed working group led by representatives of three big pharma, Bristol-Myers Squibb, GlaxoSmithKline ...
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Oral solid dosage forms are the most patient-accepted and therefore industrially relevant pharmaceutical applications, representing 80% of the market share. In that context, polymer processing techniques, such as hot melt extrusion (HME) or injection molding (IM), are increasingly used to process primary material into the final dosage forms due to several benefits (e.g., enhanced solubility or ...
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OBJECTIVE To test the ability of an assessment-driven algorithm for treatment of pediatric status asthmaticus to reduce length and cost of hospitalization. DESIGN Nonrandomized, prospective, controlled trial. SETTING Tertiary care children's hospital. PATIENTS Children aged 1 to 18 years hospitalized for status asthmaticus; 104 were treated using the asthma care algorithm (intervention) a...
متن کامل"In vitro" dissolution tests for solid oral dosage forms.
©2010 Particle Sciences, Inc. All rights reserved. the drug substance and involves two steps: dissolution and absorption (or permeability). Understanding the multi-step dissolution process is essential to proper in vitro method development. Dissolution is the process of extracting the API out of the dosage form solid-state matrix into solution within the gastrointestinal tract. Absorption is th...
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The dual release system is used to achieve both quick and sustained release effect from dosage form. The dual release action achieve by using core compressed tablet, bi-layer or multi layer tablet, IR and SR granules containing matrix tablet and capsules. Some researcher formulated dual release system by incorporating disintegrants for immediate release part and different polymers for sustained...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2014
ISSN: 0306-5251
DOI: 10.1111/bcp.12442